abstract：:We have investigated the clinical, hematological, and molecular genetic characteristics of sickle cell anemia patients from 6 populations of Andhra Pradesh, South India. Of 72 sickle cell chromosomes (HBB*S) 60 belong to characteristic Arab-Indian haplotypes, 6 to variant Arab-Indian haplotypes, 1 to a Bantu haplotype...

journal_title：Human biology

authors： Niranjan Y,Chandak GR,Veerraju P,Singh L

更新日期：1999-06-01 00:00:00

abstract：:Involvement of genetic factors in determining bone mineral density (BMD) is doubtless. However, the exact nature of the genes governing BMD variation and sources for genetic determination of BMD of different parts of bone (compact and cancellous) have not been completely studied. The results of the complex segregation...

journal_title：Human biology

authors： Livshits G,Karasik D,Pavlovsky O,Kobyliansky E

更新日期：1999-04-01 00:00:00

abstract：:Three apolipoprotein B restriction fragment length polymorphism (RFLPs) (XbaI, MspI, and EcoRI) and the signal peptide insertion-deletion polymorphism were investigated using the polymerase chain reaction in 140 individuals from 5 Brazilian Indian tribes. All studied markers were polymorphic in this ethnic group. The ...

journal_title：Human biology

authors： Kaufman L,Vargas AF,Coimbra Júnior CE,Santos RV,Salzano FM,Hutz MH

更新日期：1999-02-01 00:00:00

abstract：:We compared the global pattern of variation at two homologous microsatellites mapping to the long arm of the X chromosome (DXYS156X) and to the short arm of the Y chromosome (DXYS156Y) in humans. A single pair of oligonucleotide primers amplifies these two nonallelic loci, each of which contains polymorphism in the nu...

journal_title：Human biology

authors： Karafet T,de Knijff P,Wood E,Ragland J,Clark A,Hammer MF

更新日期：1998-12-01 00:00:00

abstract：:Eight STR systems (THO1, FABP, VWA, FES/FPS, HPRTB, F13A1, CSF1PO, and D6S366) were investigated in different ethnic groups of Argentina. Allele and genotype frequencies, power of exclusion, and discriminative power were investigated. Hardy-Weinberg expectations were calculated from heterozygosity levels. FST and G te...

journal_title：Human biology

authors： Sala A,Penacino G,Corach D

更新日期：1998-10-01 00:00:00

abstract：:GM and KM immunoglobulin (Ig) allotypes have been tested in 310 autochthonous Basques from the three subpopulations of Vizcaya, Guipúzcoa, and Alava, Spain. They are compared with allotypes occurring in autochthonous French Basques, some Pyrenean subpopulations in France, and European populations. The analysis suggest...

journal_title：Human biology

authors： Calderón R,Vidales C,Peña JA,Perez-Miranda A,Dugoujon JM

更新日期：1998-08-01 00:00:00

abstract：:Several epidemiological studies have established that elevated serum lipoprotein (a) [Lp(a)] levels are independent risk factors for coronary heart disease, stroke, and restenosis of coronary lesions in white and Asian populations. Serum Lp(a) levels vary over a 1000-fold range among individuals and are under strict g...

journal_title：Human biology

authors： Ali S,Bunker CH,Aston CE,Ukoli FA,Kamboh MI

更新日期：1998-06-01 00:00:00

abstract：:Given that the evidence of a substantial genetic contribution to cognitive ability is now convincing, the next challenge is to locate and identify the genes involved. It is likely that there are several genes, each of only small effect. Detection of such so-called quantitative trait loci contributing to polygenic trai...

journal_title：Human biology

authors： Daniels J,McGuffin P,Owen MJ,Plomin R

更新日期：1998-04-01 00:00:00

abstract：:A random sample of death records of adult males from the period 1967 to 1970 was chosen from the South Australian Registry of Births, Deaths, and Marriages. The natural parents of these individuals were identified by cross-referencing to birth certificates, and an extensive search was made of the death records for the...

journal_title：Human biology

authors： Tallis GM,Leppard P

更新日期：1997-12-01 00:00:00

abstract：:The isonymy structure of two Venezuelan states, Sucre and Táchira, is described using the surnames of the Register of Electors updated in 1991. The frequency distribution of surnames pooled together by sex was obtained for the 57 counties of Sucre and the 52 counties of Táchira, based on total population sizes of 158,...

journal_title：Human biology

authors： Rodríguez-Larralde A,Barrai I

更新日期：1997-10-01 00:00:00

abstract：:Low-molecular-weight acid phosphatase (ACP1) is a polymorphic protein-tyrosine phosphatase present in all human tissues, including adipocytes. A positive association between the low-activity ACP1*A/*A genotype and extreme body mass index has previously been shown by us in obese subjects from the population of Rome. We...

journal_title：Human biology

authors： Lucarini N,Antonacci E,Bottini N,Gloria Bottini F

更新日期：1997-08-01 00:00:00

abstract：:We examine mortality and fertility patterns of aboriginal (primarily Evenki and Keto) and Russian (i.e., nonaboriginal) populations from the Baykit District of Central Siberia for the period 1982-1994. Mortality rates in the aboriginal population of Baykit are substantially greater than those observed in the Russians ...

journal_title：Human biology

authors： Leonard WR,Keenleyside A,Ivakine E

更新日期：1997-06-01 00:00:00

abstract：:The cross-cultural study of secular trends in twinning has been of interest to students of human biology. Although recent vital statistics are likely to be more reliable, older vital records allow a long-term study of twinning trends and of the effect of epidemics on twin incidence. Here, I report the results of an in...

journal_title：Human biology

authors： Madrigal L

更新日期：1997-04-01 00:00:00

abstract：:Isoelectric focusing was used to investigate the genetic variants of the human plasma orosomucoid ORM1 and ORM2 gene loci in samples of Egyptians, Sudanese, and Qataris. The study populations were classified into 28 ORM phenotypes determined by 10 ORM1 and 9 ORM2 alleles that included 2 new alleles, designated ORM1*B1...

journal_title：Human biology

authors： Sebetan IM,Oshida S,Yuasa I,Tie J

更新日期：1997-02-01 00:00:00

abstract：:The frequency of a polymorphic mitochondrial DNA insertion into the nuclear genome was determined for 870 individuals from a geographically diverse set of 20 populations. The mtDNA insertion frequency varies significantly among populations, having a large GST value (0.178) and high heterozygosity values within populat...

journal_title：Human biology

authors： Thomas R,Zischler H,Pääbo S,Stoneking M

更新日期：1996-12-01 00:00:00

abstract：:Genetic polymorphisms of the complement components (five loci: C2, C3, C4A, C4B, and BF) have been investigated in the Telugu-speaking Hindu population of Hyderabad, Andhra Pradesh, India, and the Bangali-speaking Muslim population of Dacca, Bangladesh. The available data are compared to understand the genetic variati...

journal_title：Human biology

authors： Ad'hiah AH,Papiha SS

更新日期：1996-10-01 00:00:00

abstract：:The main goal of the present study is to elucidate the extent to which primary characteristics of bone aging are determined by major gene effects. We report the results of a complex segregation analysis of bone mineral density (BMD) and osseographic score (OS) carried out on an array of pedigrees from rural Turkmenia....

journal_title：Human biology

authors： Livshits G,Pavlovsky O,Kobyliansky E

更新日期：1996-08-01 00:00:00

abstract：:We analyze the possible effect of gene flow on the genetic structure of present-day Mexicans. For this purpose we reviewed previous admixture estimates for various Indian and Mestizo groups. Several facts seem clear: (1) There are no pure Indian groups in Mexico, because all Indian groups show variable degrees of admi...

journal_title：Human biology

authors： Lisker R,Ramírez E,Babinsky V

更新日期：1996-06-01 00:00:00

abstract：:The DNA profiles of two unrelated individuals can match (complete similarity) by chance alone. When the two individuals are related, the probability of a coincidental match is higher. Here, I deal with the probabilities of coincidental matches for both related and unrelated individuals. The derivation starts from firs...

journal_title：Human biology

authors： Li CC

更新日期：1996-04-01 00:00:00

abstract：:We evaluate the blood pressure profile in relation to selected biological, behavioral, and socioeconomic factors among the Lepchas, a tribal population of Asian origin inhabiting the Dzongu area of northern Sikkim. The results show that mean systolic and diastolic blood pressures of Lepcha adults (aged 19 years and ol...

journal_title：Human biology

authors： Mukhopadhyay B,Mukhopadhyay S,Majumder PP

更新日期：1996-02-01 00:00:00

abstract：:A meaningful comparison of the twinning rates of different populations can be hindered by several factors that may influence the rates. Chief among these factors are the sources of data from which the rates are derived and the maternal age structure of the populations. The effects of such factors were minimal when the...

journal_title：Human biology

authors： Pollard R

更新日期：1995-12-01 00:00:00

abstract：:Genetic diversity among ethnic groups is studied by comparing the genetic fingerprint of the examined groups. This index is constructed by aggregating the differential frequencies of various marker characteristics. Recent advances in the study of human biological rhythms may provide new indexes that will complement th...

journal_title：Human biology

authors： Ticher A,Zoossmann-Diskin A,Haus E,Sackett-Lundeen L,Ashkenazi IE

更新日期：1995-10-01 00:00:00

abstract：:Data related to ten protein genetic loci expressed in blood obtained from four South American black populations were compared with data from seven African countries. Estimates of admixture among South American blacks were revised, and several indexes of gene diversity and genetic distances between the 11 populations w...

journal_title：Human biology

authors： Bortolini MC,Weimer Tde A,Salzano FM,Callegari-Jacques SM,Schneider H,Layrisse Z,Bonatto SL

更新日期：1995-08-01 00:00:00

abstract：:We investigated differential sex-biased parental investment in relation to social status in 59 Kavango males from Rundu, the administrative and commercial center of the Kavango district in northern Namibia, and in 78 Kavango males from the rural areas around Rundu. Twenty-three body dimensions were used as indicators ...

journal_title：Human biology

authors： Kirchengast S,Winkler EM

更新日期：1995-04-01 00:00:00

abstract：:Preston's two-census method of demographic estimation is applied to three pairs of reconstructed censuses from the records of a migrating Mennonite church congregation covering the period 1780-1890. The three pairs of censuses correspond to three periods (1780-1790, 1850-1860, and 1880-1890) and to stays in three sett...

journal_title：Human biology

authors： Everson PM,Stevenson JC,Rogers L

更新日期：1995-02-01 00:00:00

abstract：:We studied the sex ratio (M/F) in representative populations of the main human ethnic groups, namely, US whites, US blacks, and Japanese. The data cover a period of over 50 years. For intra-ethnic comparison, we included analogous data on Italians. The populations studied show heterogeneous patterns: the US white and ...

journal_title：Human biology

authors： Ulizzi L,Zonta LA

更新日期：1994-12-01 00:00:00

abstract：:There is widespread interest in obtaining genetic samples from human populations worldwide for various studies of human genetic diversity. Many samples exist today only in the form of small, rare, irreplaceable, or archival samples, such as material from ancient bone, hair bulbs, or remnants of samples collected in th...

journal_title：Human biology

authors： Weiss KM,Buchanan AV,Daniel C,Stoneking M

更新日期：1994-10-01 00:00:00

abstract：:The polymorphism of human mitochondrial DNA (mtDNA) was studied in 118 unrelated Greeks (from northern Greece) using total blood cell DNA and the restriction enzymes HpaI, BamHI, HaeII, MspI, AvaII, and HincII. One new morph was identified for MspI (named MspI morph 18Gr) and is the result of a mutation in a previousl...

journal_title：Human biology

authors： Astrinidis A,Kouvatsi A

更新日期：1994-08-01 00:00:00

abstract：:A mismatch distribution is a tabulation of the number of pairwise differences among all DNA sequences in a sample. In a population that has been stationary for a long time these distributions from nonrecombinant DNA sequences become ragged and erratic, whereas a population that has been growing generates mismatch dist...

journal_title：Human biology

authors： Harpending HC

更新日期：1994-08-01 00:00:00

abstract：:Lipoprotein lipase (LPL) plays a critical role in the metabolism of lipoproteins because this enzyme hydrolyzes the triacylglycerides in chylomicrons and very low density lipoproteins. This process influences the production of high-density lipoprotein (HDL), which takes up tissue cholesterol for transport to the liver...

journal_title：Human biology

authors： Mitchell RJ,Earl L,Bray P,Fripp YJ,Williams J

更新日期：1994-06-01 00:00:00

abstract：:Alleles of the hypervariable human locus D17S5 were amplified by polymerase chain reaction (PCR) and categorized by length. Unlike other surveys of this locus, the products of amplification were authenticated by Southern analysis using an oligomeric probe directed to part of the 70-base-pair (bp) variable number of ta...

journal_title：Human biology

authors： Kijas JM,Fowler JC,Van Daal A

更新日期：1994-04-01 00:00:00

abstract：:The relation between TaqI restriction fragment length polymorphisms (RFLPs) of the cholesteryl ester transfer protein (CETP) gene and plasma lipid and lipoprotein phenotypes was investigated in a sample of Italian and Greek migrants of both sexes, age 40-69 years. Italians display significantly higher mean triglycerid...

journal_title：Human biology

authors： Mitchell RJ,Earl L,Williams J,Bisucci T,Gasiamis H

更新日期：1994-02-01 00:00:00

abstract：:Paleodemographic studies have seldom been attempted in sub-Saharan Africa. The Mapungubwe complex of sites in northern Transvaal (A.D. 970-1200) has yielded enough skeletal material to warrant such an investigation. The skeletal collection consists of 109 individuals (97 from K2 and 12 from Mapungubwe itself). Because...

journal_title：Human biology

authors： Henneberg M,Steyn M

更新日期：1994-02-01 00:00:00

abstract：:Colon cancer is known to be heritable in humans, but the opportunity to investigate the genetic epidemiology of cancer in nonhuman primates has been limited by the size of available populations. The cotton-top tamarin (Saguinus oedipus) colony at the Oak Ridge Associated Universities (ORAU) Marmoset Research Center is...

journal_title：Human biology

authors： Cheverud JM,Tardif S,Henke MA,Clapp NK

更新日期：1993-12-01 00:00:00

abstract：:Anthropoid phylogeny has been characterized by dramatic increases in relative brain size. Given the importance of genetic mechanisms in evolution, quantitative genetic analyses of the biological concomitants of relative brain size variation should greatly augment our understanding of this phylogenetic phenomenon. In h...

journal_title：Human biology

authors： Mahaney MC,Williams-Blangero S,Blangero J,Leland MM

更新日期：1993-12-01 00:00:00

abstract：:There has been a lack of agreement on the variation in and the correlates of menstrual cycle length in the literature. A total of 2566 women from rural and urban areas in one district of Tamil Nadu in southern India were studied prospectively to identify correlates of menstrual cycle length. Rural women had higher odd...

journal_title：Human biology

authors： Jeyaseelan L,Rao PS

更新日期：1993-08-01 00:00:00

abstract：:Restriction fragment length polymorphisms (RFLPs) at codons 2488 (XbaI), 3611 (MspI), and 4154 (EcoRI) of the apolipoprotein B gene were investigated in sample groups from Athens (Greece) and Calabria (southern Italy) to verify whether the distribution of the APOB gene variants in Calabria, where Greek colonization oc...

journal_title：Human biology

authors： De Benedictis G,Leone O,Falcone E,Rose G,Brancati C,Carotenuto L

更新日期：1993-06-01 00:00:00

abstract：:The Norse and Celtic contributions to the founding population of Iceland have been estimated previously on a pan-Icelandic basis using gene frequency data for the entire island. Accounts of the settlement of Iceland, however, suggest that different regions received different proportions of Norse and Celtic settlers, i...

journal_title：Human biology

authors： Williams JT

更新日期：1993-04-01 00:00:00

abstract：:Hematocrit values are normally higher in natives living at high altitude than in natives living at sea level. Here, we have determined the hematocrit levels in relation to adrenal androgens in children living at altitudes of 150 m and 3400 m above sea level. The data demonstrate no association between serum adrenal an...

journal_title：Human biology

authors： Góñez C,Donayre M,Villena A,Gonzales GF

更新日期：1993-02-01 00:00:00

abstract：:We summarize several studies, from the last 10 years, of temporal changes and rural-urban differences in the risk factors of cardiovascular disease (CVD) in China to indicate the influences of economic modernization. Two national blood pressure surveys have shown that the prevalence of hypertension increased from 5.1%...

journal_title：Human biology

authors： Zhai S,McGarvey ST

更新日期：1992-12-01 00:00:00